The Smile Train is an international children’s charity that provides cleft lip and cleft palate surgery to children in need, as well as providing cleft-related training to doctors.  Unlike many charities that do many different things, The Smile Train mission is focused on solving a single problem: cleft lip and palate.  Clefts are a major problem in developing countries where there are millions of children who are suffering with unrepaired clefts. Most cannot eat or speak properly, are not allowed to attend school or hold a job, and face very difficult lives filled with shame and isolation, pain and heartache.

The Smile Train mission is:
-To provide free cleft surgery for millions of poor children in developing countries.
-To provide free cleft-related training for doctors and medical professionals.

Dr. D’Antonio was a member of The Smile Train Medical Advisory Board from 2000 to 2012 and was a speaker at its inaugural meeting in the People’s Republic of China in 2001.  She has been a very active member of The Smile Train and has engaged in many volunteer activities.  She was a contributor to the Smile Train Virtual Surgery Videos Volume 2. Secondary Cleft Lip and Palate Surgery.